Author: RPW Scott
Book:Principles and Practice of Chromatography
Section:Principles Available-Stationary-Phase Chiral
Courtesy of ASTEC Inc. Figure 18 The Separation of Warfarin Isomers on a CYCLOBOND Column The cyclodextrins are produced by the partial degradation of starch followed by the enzymatic coupling of the glucose units into crystalline, homogeneous toroidal structures of different molecular sizes. Three of the most widely characterized are alpha, beta and gamma cyclodextrins which contain 6, 7 and 8 glucose units respectively. Cyclodextrins are chiral structures and the beta- cyclodextrin has 35 stereogenic centers. CYCLOBOND is a trade




