Sponsors' Messages
 Compact & intelligent
Ion Chromatography (IC) from Metrohm
The new 881/882 range space saving IC instruments have all intelligent
module functions integrated into the instruments i.e. iPump, iDetector,
iColumn technology. These guarantee precise results without errors. The
MagIC Net™ chromatography software controls all system components
and surveys all parameters that are relevant to the chromatographic analysis.
Typical applications: all waters, pharmaceuticals, chemicals, food, power,
petrochemicals & biofuels.
http://www.metrohm.co.uk/article.php?id=188 « Click here
 How to buy a LIMS or Sample Tracker
And just as important, how not to! A new free LIMS and Sample Tracking
selection guide tells you all you need to know. For your copy email matrix@autoscribe.co.uk.
Autoscribe create fully configurable web and desktop LIMS / Sample Tracking
solutions for any laboratory in any industry that can be integrated with
CDS, instruments, balances and barcode devices.
http://www.autoscribe.co.uk/requestforinfo.shtml « Click
here
 Discover the gold standard technique for chromatography
The Biochrom 30 amino acid analyzer is a dedicated instrument for clinical,
pharmaceutical, proteomics, food and feedstuff industries. Based on ion-exchange
liquid chromatography technology and using established ninhydrin colorimetry,
the state-of–the art instrument is fully integrated into a complete
bench-top, PC-controlled package.
www.biochrom.co.uk « Click
here
 Q-Adept, the New Addition to the Adept HPLC Range
Cecil Instruments, the name you can trust, have expanded the Adept HPLC
range to include Q-Adept systems. The Q-Adept range includes both quaternary
and binary low pressure mixing pumps. These space saving and compact systems
add even more versatility and modularity, to provide enormous cost savings.
http://www.cecilinstruments.com/adept-1.html « Click
here
 Two
New GCs & Whole Product Solutions from Varian
Introducing the 450-GC, 430-GC and Comprehensive Analysis Solutions:
- State-of-the-Art Performance
- Application Engineered
- Custom and Industry Standard Methods
The highly flexible, multi-channel
450-GC, when combined with powerful Galaxie™ software, industry-leading
capillary columns and Varian's 40+ years of robust application solutions,
meets all your GC analysis needs. The compact 430-GC is designed for dedicated
and routine use while offering comparable performance.
Performance
and Flexibility in One Product « Click
here
 Improved Qualitative GCMS and LCMS Data Processing
from SpectralWorks
AnalyzerPro™ simplifies the analysis of 'Unknown unknowns' with
flexible data reporting. The use of retention time, retention index, library
search and ion ratio confirmation provides corroboration of GCMS and LCMS
spectra. To see what you are missing in your MS samples request more information
and a free trial.
http://www.spectralworks.com/april08 « Click
here
 ZIC®-HILIC Separation of Polar and Hydrophilic
Compounds
The advanced technology ZIC®-HILIC separation media, designed for separation
of polar and hydrophilic compounds, have been used to develop a new analytical
methodology for gamma-Hydroxybutyric acid (GHB) in biological matrixes.
Quantification is achieved within 3 minutes using a silica based ZIC®-HILIC
column and single stage negative ESI-MS detection.
http://www.sequant.com « Click
here
 Precision, at the Speed of Prominence UFLC
Shimadzu's Prominence Ultra-Fast HPLC (UFLC) raises total system productivity
to new levels by generating high-quality, reproducible data through superior
design, engineering and quality. World-class speed, unmatched durability
and reproducibility, system flexibility - for maximum productivity, the
choice is Prominence UFLC: Data without compromise.
www.ssi.shimadzu.com/ALLC « Click
here
 Improve your selectivity options with the new member
of the Hypersil GOLD family
With the new Hypersil GOLD™ Phenyl HPLC columns you can experience:
- Excellent retention and unique selectivity for aromatic analytes
- Alternative selectivity over alkyl chain chemistries for moderately
polar compounds
- A choice of particle sizes – 1.9, 3 and 5 μm
- And like all members of the Hypersil GOLD family, outstanding
peak shape and sensitivity
Chromatogram: Antibacterials separated on a Hypersil GOLD Phenyl, 5 μm,
150 x 4.6 mm (Part Number: 25405-154630). For complete details of this application
and a complete product listing:
http://www.thermo.com « Click
here
 Capillary Flow Technology GC x GC Flow Modulator
Agilent Capillary Flow Technology's reliable, leak-free, in-oven design now provides comprehensive multidimensional chromatography, also called GC x GC, offering powerful capabilities for analyzing complex mixtures such as petrochemicals, fragrances and environmental samples. Compared to a single column separation, GC x GC can improve peak resolution and peak capacity to provide highly detailed sample characterization.
http://www.agilent.com/chem/gcxgc « Click here
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A recent paper* published in the Journal of
Chromatographic Science highlights
the trend in HPLC towards faster and more efficient columns using sub-2 micron
diameter particles. The use of very small particles for this purpose was suggested
by A. J. P. Martin as long ago as 1946 but their use demands certain equipment
characteristics that have only become available relatively recently; suitable
packing techniques for such particles also had to be developed. To some extent
these requisites are still a challenge today. As the solute bands are very
narrow and are eluted very fast, carefully designed injection equipment must
be available to ensure the band-width of the sample on injection is kept exceedingly
small and that neither the dispersion in the detector sensor nor the response
time of the electronics contribute significantly to the solute band-width.
Injector-column and column-detector connections must also be constructed to
minimize extra column dispersion. The authors claim that they restricted the
standard deviation of a peak resulting solely from extra column dispersion
to about 14 microliters. This value is useful but could be made considerably
smaller by careful equipment design. The paper describes the use of the system
for a number of pharmaceutical applications.
Several readers have written to ask questions on specific chromatography problems
and separations. I don't have the answers to most of the questions so I recommend
that they visit www.chromatographyforum.com which is a very active discussion
group supported by four equipment suppliers and LC*GC magazine.
It is the best site I have found for getting advice about specific separations
or equipment problems.