Chlorthalidone by Cyclobond I 2000 RSP Column

The enantiomers of the diuretic drug chlorthalidone were separated by reversed phase HPLC using a Cyclobond I 2000 column and detected by UV at 254nm.

Chlorthalidone, Astec Application Report 4004

Chlorthalidone, CAS No. 77-36-1, a diuretic drug was separated into its two respective enantiomers by isocratic elution in around 25 minutes by reversed phase HPLC on an Astec Cyclobond I 2000 RSP column (250 x 4.6mm, Part No. 20324) using water, acetonitrile, (5:95), 1% TEAA, pH 4.1. The enantiomers were detected by UV at 254nm.