Separation of Two Neuroleptics by HPLC

Two neuroleptic compounds in rabbit plasma were separated using a GROM-SIL 120 CN-3 CP column and detected by electrochemical detection at 850mV.

Neuroleptics, Grom Application Number 06034

Two neuroleptic compounds in rabbit plasma were separated using a GROM-SIL 120 CN-3 CP column (50 x 4mm, Part No. GSCN30512S) by isocratic elution with 0.1M sodium acetate, pH 5.0 and acetonitrile 36/64 in around 15 minutes and detected by electrochemical detection at 850mV. The neuroleptic compounds separated were chlorpromazine and promazine.