Flow Programmers
Flow programming is a procedure where the mobile phase flow-rate is increased during chromatographic development. If the mobile phase is compressible the relationship between retention volume, flow rate and inlet pressure is given by,
(1)
| Where (Vr) | is the true retention volume of the solute, |
| (Vr(0)) | is the retention volume measured at the outlet. |
| and (g) | is the inlet/outlet pressure ratio |
(for the derivation of this equation see The Thermodynamics of Chromatography)
Thus, 
Now, from
The Thermodynamics of Chromatography
where (e) is a constant
Thus, 
(2)
If (g) is large compared with unity, Then
